On 15–16 October 2026, the University of Montenegro in Podgorica hosted the 5th International Scientific Symposium “Days of Scientific Diaspora 2026“, where Prof. Sergej Đuranović from Brown University, a member of the BIOCAN research team, gave a talk.
In his talk, “RAPPL-Seq provides insights into protein synthesis from clinically relevant samples“, Prof. Đuranović presented a new approach to ribosome profiling, a method that shows which proteins a cell is actively producing. Unlike conventional approaches, RAPPL-Seq requires only small amounts of biological material, which makes it suitable for patient samples.
The method uses magnetic bead-based affinity capture to efficiently isolate ribosome-protected RNA fragments. It was applied to biopsy samples of glioblastoma and adjacent non-tumour brain tissue, demonstrating its potential for studying protein synthesis directly in clinical material.
The research is associated with an international patent application filed by Washington University in St. Louis, with Prof. Đuranović named as one of the co-inventors.
We are proud to have Prof. Đuranović as part of the BIOCAN team and congratulate him on his excellent presentation.
